The Lady Techsters (30-4), seeded third in the East Regional, advanced to the round of 16 for the ninth straight year, all coming after being host of a subregional
Walker, the Techsters' leading scorer, had a season-low two points in the first round, though it was hardly a problem for the Techsters as they beat Georgia State by 36.
Walker, however, was so upset with her performance that she cried when she was taken out of the game for good.
It took the 6-foot-2 junior all of 15 seconds to match her first-round point total, scoring on Louisiana Tech's first possession. She followed that up by blocking TCU's first shot and the Techsters were on their way to an 18th consecutive victory.
After Essence Perry scored Louisiana Tech's first eight points of the second half, Walker scored the next six as the Techsters opened up a 52-36 lead.
A turnaround jumper by Walker with 3:30 left made it 69-49.
Tricia Payne scored 13 points to lead 11th-seeded TCU (25-8), which could not hold up against Tech's defensive pressure and dominant inside game.
Louisiana Tech's post players scored 20 of the team's first 22 points. The Techsters made 53 percent of their field goal attempts in the first half, rarely shooting from beyond 8 feet, and held a 38-27 lead at the break.
Louisiana Tech will meet Missouri in the East Regional semifinals in Pittsburgh.